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Chemical structure of ORM-10103

GC36814

ORM-10103

Also known as 5-nitro-2-[(2-phenyl-3,4-dihydro-2H-chromen-6-yl)oxy]pyridine

ORM-10103 is a specific inhibitor of the Na+/Ca2+ exchanger (NCX), which decreases the NCX current with estimated IC50s of 55 and 67 nM at -80 and at 20 mV, respectively

ChemicalCAS488847-28-5MW348.35FormulaC20H16N2O4
CAS number
488847-28-5
Molecular weight
348.35
Formula
C20H16N2O4
Solubility
DMSO: 250 mg/mL (717·67 mM)
InChIKey
GZONLGPIHCCJOI-UHFFFAOYSA-N
Catalogue number
GC36814
Brand
GLPBIO
Computed properties PubChem CID 17978512 · XLogP 4.4 · TPSA 77.2 Ų · H-bond donors 0
XLogP
4.4
TPSA
77.2 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
3
Heavy atoms
26

SMILES C1CC2=C(C=CC(=C2)OC3=NC=C(C=C3)[N+](=O)[O-])OC1C4=CC=CC=C4

Computed descriptors from PubChem (CID 17978512), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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