GC73681
TNG-462
Also known as N-(6-amino-5-ethyl-3-pyridinyl)-2-[(2R,5S)-5-methyl-2-[2-(1-methylpiperidin-4-yl)-1,3-benzothiazol-5-yl]piperidin-1-yl]-2-oxoacetamide
TNG-462 is an orally active and selective PRMT5 inhibitor with anti-tumor activity against metlthioadenosine phosphorylase (MTAP) deficiency and/or metlthioadenosine (MTA) accumulation cancers
ChemicalCAS2760483-96-1MW520.69FormulaC28H36N6O2S
- CAS number
- 2760483-96-1
- Molecular weight
- 520.69
- Formula
- C28H36N6O2S
- Solubility
- DMSO ： 100 mg/mL (192·05 mM; Need ultrasonic)
- InChIKey
- DHAGMIPSRSPWSH-GAJHUEQPSA-N
- Catalogue number
- GC73681
- Brand
- GLPBIO
Computed properties PubChem CID 164752829 · XLogP 4.3 · TPSA 133 Ų · H-bond donors 2
- XLogP
- 4.3
- TPSA
- 133 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Rotatable bonds
- 4
- Heavy atoms
- 37
SMILES CCC1=C(N=CC(=C1)NC(=O)C(=O)N2C[C@H](CC[C@@H]2C3=CC4=C(C=C3)SC(=N4)C5CCN(CC5)C)C)N
Computed descriptors from PubChem (CID 164752829), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il