GC65328
TNIK-IN-3
Also known as 4-[(4-fluorophenyl)methyl]-8-(1H-pyrrolo[2,3-b]pyridin-5-yl)-2,3-dihydro-1,4-benzoxazepin-5-one
TNIK-IN-3 is a potent, selective and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK), with an IC50 of 0·026 μM· TNIK-IN-3 could also inhibit Flt4 (IC50=0·030 μM), Flt1 (IC50=0·191 μM) and DRAK1 (IC50=0·411 μM)· TNIK-IN-3 can be used for the research of colorectal cancer
ChemicalCAS2754265-25-1MW387.41FormulaC23H18FN3O2
- CAS number
- 2754265-25-1
- Molecular weight
- 387.41
- Formula
- C23H18FN3O2
- Solubility
- DMSO ： 83·33 mg/mL (215·10 mM; Need ultrasonic)
- InChIKey
- UVLOISNMRLZTPF-UHFFFAOYSA-N
- Catalogue number
- GC65328
- Brand
- GLPBIO
Computed properties PubChem CID 162641720 · XLogP 3.7 · TPSA 58.2 Ų · H-bond donors 1
- XLogP
- 3.7
- TPSA
- 58.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Rotatable bonds
- 3
- Heavy atoms
- 29
SMILES C1COC2=C(C=CC(=C2)C3=CN=C4C(=C3)C=CN4)C(=O)N1CC5=CC=C(C=C5)F
Computed descriptors from PubChem (CID 162641720), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il