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Chemical structure of TNG260

GC70040

TNG260

Also known as N-[2-amino-5-(4-fluorophenyl)phenyl]-4-(methylsulfonimidoyl)benzamide

TNG260 is a selective CoREST deacetylase (CoreDAC) inhibitor· TNG260 selectively inhibits HDAC1 10 times more than HDAC3· TNG260 leads to the inhibition of HDAC1 and reverses anti-PD1 resistance driven by STK11 deficiency· TNG260 reduces tumor infiltration of neutrophils· TNG260 exhibits immune-mediated cell killing

ChemicalCAS2935964-98-8MW383.44FormulaC20H18FN3O2S
CAS number
2935964-98-8
Molecular weight
383.44
Formula
C20H18FN3O2S
InChIKey
JPFMYSJUFUEHBI-HHHXNRCGSA-N
Catalogue number
GC70040
Brand
GLPBIO
Computed properties PubChem CID 168264922 · XLogP 4.3 · TPSA 104 Ų · H-bond donors 3
XLogP
4.3
TPSA
104 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
27

SMILES C[S@@](=N)(=O)C1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C3=CC=C(C=C3)F)N

Computed descriptors from PubChem (CID 168264922), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.