Loading...
Chemical structure of ARD-1676

GC73613

ARD-1676

Also known as 2-chloro-4-[(3S)-8-[4-[4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-5,7-dihydropyrrolo[3,4-f]isoindol-6-yl]methyl]piperidine-1-carbonyl]phenyl]-3-methyl-2,8-diazaspiro[4.5]decan-2-yl]benzonitrile

ARD-1676 is an orally available androgen receptor (AR) PROTAC degrader, consisting of AR ligand and cereblon ligand

ChemicalCAS2632305-36-1MW788.33FormulaC44H46ClN7O5
CAS number
2632305-36-1
Molecular weight
788.33
Formula
C44H46ClN7O5
Solubility
DMSO ： 100 mg/mL (126·85 mM; Need ultrasonic)
InChIKey
GAXWAKXJBZHVQF-ZVENJKCTSA-N
Catalogue number
GC73613
Brand
GLPBIO
Computed properties PubChem CID 156180706 · XLogP 4.9 · TPSA 137 Ų · H-bond donors 1
XLogP
4.9
TPSA
137 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
6
Heavy atoms
57

SMILES C[C@H]1CC2(CCN(CC2)C3=CC=C(C=C3)C(=O)N4CCC(CC4)CN5CC6=CC7=C(C=C6C5)C(=O)N(C7=O)C8CCC(=O)NC8=O)CN1C9=CC(=C(C=C9)C#N)Cl

Computed descriptors from PubChem (CID 156180706), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.