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Chemical structure of ARD-69

GC72850

ARD-69

Also known as (2S,4R)-N-[(1S)-3-[4-[4-[2-[4-[[3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]carbamoyl]phenyl]ethynyl]piperidin-1-yl]piperidin-1-yl]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]-3-oxopropyl]-1-[(2S)-2-[(1-fluorocyclopropanecarbonyl)amino]-3,3-dimethylbutanoyl]-4-hydroxypyrrolidine-2-carboxamide

ARD-69 (compound 34) is a potent PROTAC androgen receptor degrader

ChemicalCAS2316837-10-0MW1129.82FormulaC62H74ClFN8O7S
CAS number
2316837-10-0
Molecular weight
1129.82
Formula
C62H74ClFN8O7S
Solubility
DMSO ： ≥ 200 mg/mL (177·02 mM)
InChIKey
CWGVEMFBQJUWLU-SKTBPLDYSA-N
Catalogue number
GC72850
Brand
GLPBIO
Computed properties PubChem CID 137321163 · XLogP 9.3 · TPSA 226 Ų · H-bond donors 4
XLogP
9.3
TPSA
226 Ų
H-bond donors
4
H-bond acceptors
12
Rotatable bonds
16
Heavy atoms
80

SMILES CC1=C(SC=N1)C2=CC=C(C=C2)[C@H](CC(=O)N3CCC(CC3)N4CCC(CC4)C#CC5=CC=C(C=C5)C(=O)NC6C(C(C6(C)C)OC7=CC(=C(C=C7)C#N)Cl)(C)C)NC(=O)[C@@H]8C[C@H](CN8C(=O)[C@H](C(C)(C)C)NC(=O)C9(CC9)F)O

Computed descriptors from PubChem (CID 137321163), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.