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Chemical structure of HPK1-IN-34

GC73438

HPK1-IN-34

Also known as 4-[3-[[2-amino-5-(2-piperidin-4-yl-1,3-thiazol-5-yl)-3-pyridinyl]oxymethyl]phenyl]-2-methylbut-3-yn-2-ol

HPK1-IN-34 (Compound 143) is a Hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 of ＜100 nM

ChemicalCAS2380300-99-0MW448.58FormulaC25H28N4O2S
CAS number
2380300-99-0
Molecular weight
448.58
Formula
C25H28N4O2S
Solubility
DMSO ： 25 mg/mL (55·73 mM; ultrasonic and warming and heat to 60°C)
InChIKey
MKDLEIMJLNBFJO-UHFFFAOYSA-N
Catalogue number
GC73438
Brand
GLPBIO
Computed properties PubChem CID 156214993 · XLogP 2.9 · TPSA 122 Ų · H-bond donors 3
XLogP
2.9
TPSA
122 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
32

SMILES CC(C)(C#CC1=CC=CC(=C1)COC2=C(N=CC(=C2)C3=CN=C(S3)C4CCNCC4)N)O

Computed descriptors from PubChem (CID 156214993), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.