Loading...
Chemical structure of HPK1-IN-19

GC69238

HPK1-IN-19

Also known as 4-N-(2-dimethylphosphorylphenyl)-2-N-(6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-5-(1-methylpyrazol-4-yl)pyrimidine-2,4-diamine

KIF18A-IN-1 is an inhibitor of hematopoietic progenitor kinase 1 (HPK1), and more information can be found in compound I-47 in patent document WO2018102366A1

ChemicalCAS2227609-33-6MW517.56FormulaC27H32N7O2P
CAS number
2227609-33-6
Molecular weight
517.56
Formula
C27H32N7O2P
Solubility
DMSO ： 100 mg/mL (193·21 mM; Need ultrasonic)
InChIKey
AZENVIBXSMLBQC-UHFFFAOYSA-N
Catalogue number
GC69238
Brand
GLPBIO
Computed properties PubChem CID 134564648 · XLogP 3.3 · TPSA 97.2 Ų · H-bond donors 2
XLogP
3.3
TPSA
97.2 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
37

SMILES CN1CCC2=CC(=C(C=C2C1)NC3=NC=C(C(=N3)NC4=CC=CC=C4P(=O)(C)C)C5=CN(N=C5)C)OC

Computed descriptors from PubChem (CID 134564648), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.