Loading...
Chemical structure of HPK1-IN-4

GC63569

HPK1-IN-4

Also known as 4-[2-(hydroxymethyl)anilino]-2-[(6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrimidine-5-carboxamide

HPK1-IN-4 (comp 22) is a HPK1 (MAPK41) inhibitor (IC50 of 0·061 nM) as preclinical immunotherapy tool compound

ChemicalCAS2739844-28-9MW434.49FormulaC23H26N6O3
CAS number
2739844-28-9
Molecular weight
434.49
Formula
C23H26N6O3
InChIKey
BNZFLUIBCNIAJW-UHFFFAOYSA-N
Catalogue number
GC63569
Brand
GLPBIO
Computed properties PubChem CID 155925915 · XLogP 2.3 · TPSA 126 Ų · H-bond donors 4
XLogP
2.3
TPSA
126 Ų
H-bond donors
4
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
32

SMILES CN1CCC2=CC(=C(C=C2C1)NC3=NC=C(C(=N3)NC4=CC=CC=C4CO)C(=O)N)OC

Computed descriptors from PubChem (CID 155925915), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.