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Chemical structure of NXPZ-2

GC71072

NXPZ-2

Also known as 2-[[4-[(2-amino-2-oxoethyl)-(4-methoxyphenyl)sulfonylamino]naphthalen-1-yl]-(4-aminophenyl)sulfonylamino]acetamide

NXPZ-2 is an orally active Keap1-Nrf2 protein-protein interaction (PPI) inhibitor with a Ki value of 95 nM, EC50 value of 120 and 170 nM

ChemicalCAS2254492-08-3MW597.66FormulaC27H27N5O7S2
CAS number
2254492-08-3
Molecular weight
597.66
Formula
C27H27N5O7S2
Solubility
DMSO ： 100 mg/mL (167·32 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
DFIZGWXPFCOCFG-UHFFFAOYSA-N
Catalogue number
GC71072
Brand
GLPBIO
Computed properties PubChem CID 164513524 · XLogP 1.8 · TPSA 213 Ų · H-bond donors 3
XLogP
1.8
TPSA
213 Ų
H-bond donors
3
H-bond acceptors
10
Rotatable bonds
11
Heavy atoms
41

SMILES COC1=CC=C(C=C1)S(=O)(=O)N(CC(=O)N)C2=CC=C(C3=CC=CC=C32)N(CC(=O)N)S(=O)(=O)C4=CC=C(C=C4)N

Computed descriptors from PubChem (CID 164513524), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.