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Chemical structure of PF-00489791

GC70901

PF-00489791

Also known as 1-(2-ethoxyethyl)-5-[ethyl(methyl)amino]-7-[(4-methyl-2-pyridinyl)amino]-N-methylsulfonylpyrazolo[4,5-d]pyrimidine-3-carboxamide

PF-00489791 (PF-489791) is a potent inhibitor of phosphodiesterase 5A with IC50 of 1·5 nM

ChemicalCAS853003-48-2MW476.55FormulaC20H28N8O4S
CAS number
853003-48-2
Molecular weight
476.55
Formula
C20H28N8O4S
Solubility
DMSO ： 12·5 mg/mL (26·23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
ZUHZNKJIJDAJFD-UHFFFAOYSA-N
Catalogue number
GC70901
Brand
GLPBIO
Computed properties PubChem CID 11465695 · XLogP 1.6 · TPSA 153 Ų · H-bond donors 2
XLogP
1.6
TPSA
153 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
10
Heavy atoms
33

SMILES CCN(C)C1=NC2=C(C(=N1)NC3=NC=CC(=C3)C)N(N=C2C(=O)NS(=O)(=O)C)CCOCC

Computed descriptors from PubChem (CID 11465695), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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