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Chemical structure of PF-01247324

GC19281

PF-01247324

Also known as 6-amino-N-methyl-5-(2,3,5-trichlorophenyl)pyridine-2-carboxamide

PF-01247324 is a selective and orally bioavailable Nav1·8 channel blocker with an IC50 of 196 nM for recombinant human Nav1·8 channel

ChemicalCAS875051-72-2MW330.6FormulaC13H10Cl3N3O
CAS number
875051-72-2
Molecular weight
330.6
Formula
C13H10Cl3N3O
Solubility
DMSO ： ≥ 30 mg/mL (90·74 mM)
InChIKey
HPIUHDCRVYDAEJ-UHFFFAOYSA-N
Catalogue number
GC19281
Brand
GLPBIO
Computed properties PubChem CID 11659955 · XLogP 3.6 · TPSA 68 Ų · H-bond donors 2
XLogP
3.6
TPSA
68 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
2
Heavy atoms
20

SMILES CNC(=O)C1=NC(=C(C=C1)C2=C(C(=CC(=C2)Cl)Cl)Cl)N

Computed descriptors from PubChem (CID 11659955), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.