GC74783
PF-00446687 free base
Also known as [(3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl]-[(3R,5S)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl]methanone
PF-00446687 is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 ± 1 nM
ChemicalCAS862281-92-3MW470.59FormulaC28H36F2N2O2
- CAS number
- 862281-92-3
- Molecular weight
- 470.59
- Formula
- C28H36F2N2O2
- Solubility
- DMSO： 62·5 mg/mL (132·81 mM; Need ultrasonic)
- InChIKey
- WHPJOAUPIZDJNX-YTEQHECZSA-N
- Catalogue number
- GC74783
- Brand
- GLPBIO
Computed properties PubChem CID 11328898 · XLogP 4.5 · TPSA 43.8 Ų · H-bond donors 1
- XLogP
- 4.5
- TPSA
- 43.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Rotatable bonds
- 4
- Heavy atoms
- 34
SMILES C[C@@H]1CN(C[C@@H](C1(C2=CC=CC=C2)O)C)C(=O)[C@@H]3CN(C[C@H]3C4=C(C=C(C=C4)F)F)C(C)(C)C
Computed descriptors from PubChem (CID 11328898), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il