Loading...
Chemical structure of PF-00562271

GC14767

PF-00562271

Also known as benzenesulfonic acid;N-methyl-N-[3-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]-2-pyridinyl]methanesulfonamide

PF-562271 (VS-6062) besylate is a potent ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase, with an IC50 of 1·5 nM and 13 nM, respectively

ChemicalCAS939791-38-5MW665.66FormulaC21H20F3N7O3S·C6H6O3S
CAS number
939791-38-5
Molecular weight
665.66
Formula
C21H20F3N7O3S·C6H6O3S
Solubility
≥ 11·1mg/mL in DMSO with gentle warming
InChIKey
LKLWTLXTOVZFAE-UHFFFAOYSA-N
Catalogue number
GC14767
Brand
GLPBIO
Computed properties PubChem CID 16118986 · TPSA 200 Ų · H-bond donors 4 · H-bond acceptors 15
TPSA
200 Ų
H-bond donors
4
H-bond acceptors
15
Rotatable bonds
8
Heavy atoms
45

SMILES CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C.C1=CC=C(C=C1)S(=O)(=O)O

Computed descriptors from PubChem (CID 16118986), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.