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Chemical structure of HIF-2α agonist 2

GC69226

HIF-2α agonist 2

Also known as N-(3,5-dibromophenyl)-1,1-dioxo-1,2-benzothiazol-3-amine

HIF-2α agonist 2 (compound 10) is a HIF-2α activator with an EC50 value of 1·68 μM at a dose of 20 μM· HIF-2α agonist 2 has no cytotoxicity on 786-O-HRE-Luc cells· It can be used for oxygen metabolism research

ChemicalCAS2750141-15-0MW416.09FormulaC13H8Br2N2O2S
CAS number
2750141-15-0
Molecular weight
416.09
Formula
C13H8Br2N2O2S
Solubility
DMSO ： 100 mg/mL (240·33 mM; ultrasonic and warming and heat to 60°C)
InChIKey
NYIUNIQAWCQVNX-UHFFFAOYSA-N
Catalogue number
GC69226
Brand
GLPBIO
Computed properties PubChem CID 164617432 · XLogP 3.1 · TPSA 66.9 Ų · H-bond donors 1
XLogP
3.1
TPSA
66.9 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
2
Heavy atoms
20

SMILES C1=CC=C2C(=C1)C(=NS2(=O)=O)NC3=CC(=CC(=C3)Br)Br

Computed descriptors from PubChem (CID 164617432), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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