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Chemical structure of HIF-1α-IN-2

GC66464

HIF-1α-IN-2

Also known as 7-methoxy-2-methyl-N-[3-(2-methyl-1,3-thiazol-4-yl)phenyl]quinolin-4-amine

HIF-1α-IN-2 is an effective HIF-1α inhibitor with anticancer potencies (IC50s of 28 nM and 15 nM in MDA-MB-231 and MiaPaCa-2 cells, respectively)· HIF-1α-IN-2 suppresses HIF-1α expression by blocking transcription and protein translation

ChemicalCAS2762315-06-8MW361.46FormulaC21H19N3OS
CAS number
2762315-06-8
Molecular weight
361.46
Formula
C21H19N3OS
Solubility
DMSO : 25 mg/mL
InChIKey
ILYYBJSTMKDZND-UHFFFAOYSA-N
Catalogue number
GC66464
Brand
GLPBIO
Computed properties PubChem CID 163196195 · XLogP 5.2 · TPSA 75.3 Ų · H-bond donors 1
XLogP
5.2
TPSA
75.3 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
26

SMILES CC1=CC(=C2C=CC(=CC2=N1)OC)NC3=CC=CC(=C3)C4=CSC(=N4)C

Computed descriptors from PubChem (CID 163196195), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.