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Chemical structure of HIF-2α-IN-1

GC31358

HIF-2α-IN-1

Also known as 3-[[(3R)-4-(difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-dioxo-3H-1-benzothiophen-5-yl]oxy]-5-fluorobenzonitrile

HIF-2α-IN-1 is a HIF-2α inhibitor has an IC50 of less than 500 nM in HIF-2α scintillation proximity assay

ChemicalCAS1799948-06-3MW405.3FormulaC16H8F5NO4S
CAS number
1799948-06-3
Molecular weight
405.3
Formula
C16H8F5NO4S
Solubility
DMSO ： 100 mg/mL (246·73 mM; Need ultrasonic)
InChIKey
HZDKYXAZAPXCKQ-CQSZACIVSA-N
Catalogue number
GC31358
Brand
GLPBIO
Computed properties PubChem CID 91810395 · XLogP 2.8 · TPSA 95.8 Ų · H-bond donors 1
XLogP
2.8
TPSA
95.8 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
3
Heavy atoms
27

SMILES C1=CC2=C([C@H](C(S2(=O)=O)(F)F)O)C(=C1OC3=CC(=CC(=C3)C#N)F)C(F)F

Computed descriptors from PubChem (CID 91810395), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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