Loading...
Chemical structure of BI-4142

GC68762

BI-4142

Also known as 1-[4-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]pyrimido[5,4-d]pyrimidin-6-yl]piperazin-1-yl]prop-2-en-1-one

BI-4142 is an effective, highly selective, orally active HER2 inhibitor with an IC50 value of 5 nM

ChemicalCAS2682003-36-5MW521.57FormulaC28H27N9O2
CAS number
2682003-36-5
Molecular weight
521.57
Formula
C28H27N9O2
Solubility
DMSO ： 100 mg/mL (191·73 mM; Need ultrasonic)
InChIKey
JKBYBPNRTMHEGS-UHFFFAOYSA-N
Catalogue number
GC68762
Brand
GLPBIO
Computed properties PubChem CID 156821183 · XLogP 3.5 · TPSA 114 Ų · H-bond donors 1
XLogP
3.5
TPSA
114 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
6
Heavy atoms
39

SMILES CC1=C(C=CC(=C1)NC2=NC=NC3=CN=C(N=C32)N4CCN(CC4)C(=O)C=C)OC5=CC6=C(C=C5)N(C=N6)C

Computed descriptors from PubChem (CID 156821183), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.