GC19068
BI-409306
Also known as 1-(oxan-4-yl)-6-(pyridin-2-ylmethyl)-5H-pyrazolo[5,4-d]pyrimidin-4-one
BI-409306 (BI-409306) is a potent and selective PDE9A inhibitor, with an IC50 of 52 nM, and shows weak activity against other PDEs, such as PDE1A (IC50, 1·4 μM), PDE1C (IC50, 1·0 μM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A (IC50 all > 10 μM); BI-409306 can be used in the research of memory enhancement in CNS disorders
ChemicalCAS1189767-28-9MW311.34FormulaC16H17N5O2
- CAS number
- 1189767-28-9
- Molecular weight
- 311.34
- Formula
- C16H17N5O2
- Solubility
- DMSO ： ≥ 75 mg/mL (240·89 mM)
- InChIKey
- BZTIJCSHNVZMES-UHFFFAOYSA-N
- Catalogue number
- GC19068
- Brand
- GLPBIO
Computed properties PubChem CID 135908617 · XLogP 0.2 · TPSA 81.4 Ų · H-bond donors 1
- XLogP
- 0.2
- TPSA
- 81.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Rotatable bonds
- 3
- Heavy atoms
- 23
SMILES C1COCCC1N2C3=C(C=N2)C(=O)NC(=N3)CC4=CC=CC=N4
Computed descriptors from PubChem (CID 135908617), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il