Loading...
Chemical structure of BI-4464

GC34488

BI-4464

Also known as 3-methoxy-N-(1-methylpiperidin-4-yl)-4-[[4-[(3-oxo-1,2-dihydroinden-4-yl)oxy]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide

BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM· A PTK2 ligand for PROTAC

ChemicalCAS1227948-02-8MW555.55FormulaC28H28F3N5O4
CAS number
1227948-02-8
Molecular weight
555.55
Formula
C28H28F3N5O4
Solubility
DMSO ： 16·67 mg/mL (30·01 mM)
InChIKey
QUSSZSMDFABHLI-UHFFFAOYSA-N
Catalogue number
GC34488
Brand
GLPBIO
Computed properties PubChem CID 58522530 · XLogP 4.4 · TPSA 106 Ų · H-bond donors 2
XLogP
4.4
TPSA
106 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
7
Heavy atoms
40

SMILES CN1CCC(CC1)NC(=O)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC5=C4C(=O)CC5)C(F)(F)F)OC

Computed descriptors from PubChem (CID 58522530), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.