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Chemical structure of NRX-103095

GC65916

NRX-103095

Also known as 4-(2,6-dichlorophenyl)sulfanyl-N-[3-(dimethylcarbamoyl)phenyl]-2-oxo-6-(trifluoromethyl)-1H-pyridine-3-carboxamide

NRX-103095 is an enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP· NRX-103095 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 163 nM

ChemicalCAS2763260-38-2MW530.35FormulaC22H16Cl2F3N3O3S
CAS number
2763260-38-2
Molecular weight
530.35
Formula
C22H16Cl2F3N3O3S
InChIKey
BGEHEUAOZPAMKC-UHFFFAOYSA-N
Catalogue number
GC65916
Brand
GLPBIO
Computed properties PubChem CID 162641002 · XLogP 4.6 · TPSA 104 Ų · H-bond donors 2
XLogP
4.6
TPSA
104 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
34

SMILES CN(C)C(=O)C1=CC(=CC=C1)NC(=O)C2=C(C=C(NC2=O)C(F)(F)F)SC3=C(C=CC=C3Cl)Cl

Computed descriptors from PubChem (CID 162641002), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.