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Chemical structure of JAK2-IN-6

GC65405

JAK2-IN-6

Also known as (4-amino-2-anilino-1,3-thiazol-5-yl)-(5-chlorothiophen-2-yl)methanone

JAK2-IN-6, a multiple-substituted aminothiazole derivative, is a potent and selective JAK2 inhibitor with an IC50 of 22·86 μg/mL· JAK2-IN-6 shows no activity against JAK1 and JAK3· JAK2-IN-6 has anti-proliferative effect against cancer cells

ChemicalCAS353512-04-6MW335.83FormulaC14H10ClN3OS2
CAS number
353512-04-6
Molecular weight
335.83
Formula
C14H10ClN3OS2
InChIKey
OFSYMZBCAABWIK-UHFFFAOYSA-N
Catalogue number
GC65405
Brand
GLPBIO
Computed properties PubChem CID 931284 · XLogP 5.7 · TPSA 124 Ų · H-bond donors 2
XLogP
5.7
TPSA
124 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
21

SMILES C1=CC=C(C=C1)NC2=NC(=C(S2)C(=O)C3=CC=C(S3)Cl)N

Computed descriptors from PubChem (CID 931284), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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