GC65190
CDK4/6-IN-11
Also known as N-[4-[4-[6-[(6-acetyl-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]piperazin-1-yl]butyl]-2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetamide
CDK4/6-IN-11 is a potent PROTAC CDK4/6 degrader
ChemicalCAS2139329-47-6MW831.92FormulaC43H49N11O7
- CAS number
- 2139329-47-6
- Molecular weight
- 831.92
- Formula
- C43H49N11O7
- Solubility
- DMSO ： 25 mg/mL (30·05 mM; Need ultrasonic)
- InChIKey
- AWPNCYPNCSCZFL-UHFFFAOYSA-N
- Catalogue number
- GC65190
- Brand
- GLPBIO
Computed properties PubChem CID 132020044 · XLogP 2.8 · TPSA 219 Ų · H-bond donors 4
- XLogP
- 2.8
- TPSA
- 219 Ų
- H-bond donors
- 4
- H-bond acceptors
- 14
- Rotatable bonds
- 14
- Heavy atoms
- 61
SMILES CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCN(CC4)CCCCNC(=O)CNC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O)C8CCCC8)C(=O)C
Computed descriptors from PubChem (CID 132020044), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il