GC35633
CDK4/6-IN-2
Also known as 5-[(4-ethylpiperazin-1-yl)methyl]-N-[5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)-2-pyridinyl]pyrimidin-2-amine
CDK4/6-IN-2 is a potent CDK4 and CDK6 inhibitor extracted from patent US20180000819A1, Compound 1, has IC50s of 2·7 and 16 nM for CDK4 and CDK6, respectively
ChemicalCAS1800506-48-2MW506.59FormulaC27H32F2N8
- CAS number
- 1800506-48-2
- Molecular weight
- 506.59
- Formula
- C27H32F2N8
- Solubility
- DMSO： 5·2 mg/mL (10·26 mM)
- InChIKey
- CMOYPFUEZDEQEH-UHFFFAOYSA-N
- Catalogue number
- GC35633
- Brand
- GLPBIO
Computed properties PubChem CID 91820696 · XLogP 3.8 · TPSA 75 Ų · H-bond donors 1
- XLogP
- 3.8
- TPSA
- 75 Ų
- H-bond donors
- 1
- H-bond acceptors
- 9
- Rotatable bonds
- 7
- Heavy atoms
- 37
SMILES CCN1CCN(CC1)CC2=CN=C(N=C2)NC3=NC=C(C(=C3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F
Computed descriptors from PubChem (CID 91820696), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il