GC65116
GA-017
Also known as 1-[(Z)-1-(2,4-dihydroxy-3-methylphenyl)propylideneamino]-3-[(3-hydroxyphenyl)methyl]urea
GA-017 is a potent and selective LATS1 and LATS2 (large tumor suppressor kinase 1/2) inhibitor, with IC50 values of 4·10 and 3·92 nM, respectively· GA-017 is an activator of cell proliferation· GA-017 promotes YAP/TAZ activation and nuclear translocation· GA-017 promotes cell growth under 3D culture conditions· GA-017 enhances the ex vivo formation of mouse intestinal organoids
ChemicalCAS2351906-74-4MW343.38FormulaC18H21N3O4
- CAS number
- 2351906-74-4
- Molecular weight
- 343.38
- Formula
- C18H21N3O4
- Solubility
- DMSO ： 20·83 mg/mL (60·66 mM; ultrasonic and warming and heat to 80°C)
- InChIKey
- FBCPIOAXERAOIA-HKWRFOASSA-N
- Catalogue number
- GC65116
- Brand
- GLPBIO
Computed properties PubChem CID 147467531 · XLogP 2.5 · TPSA 114 Ų · H-bond donors 5
- XLogP
- 2.5
- TPSA
- 114 Ų
- H-bond donors
- 5
- H-bond acceptors
- 5
- Rotatable bonds
- 5
- Heavy atoms
- 25
SMILES CC/C(=N/NC(=O)NCC1=CC(=CC=C1)O)/C2=C(C(=C(C=C2)O)C)O
Computed descriptors from PubChem (CID 147467531), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il