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Chemical structure of GATA4-NKX2-5-IN-1

GC25450

GATA4-NKX2-5-IN-1

Also known as N-[4-(diethylamino)phenyl]-5-methyl-3-phenyl-1,2-oxazole-4-carboxamide

GATA4-NKX2-5-IN-1 (3i-1000) is a small-molecule compound inhibiting GATA4 and NKX2-5 transcriptional synergy with IC50 of 3 uM

ChemicalCAS544681-96-1MW349.43FormulaC21H23N3O2
CAS number
544681-96-1
Molecular weight
349.43
Formula
C21H23N3O2
Solubility
DMSO: 70 mg/mL (200·33 mM);Water: Insoluble;Ethanol: 9 mg/mL (25·76 mM)
InChIKey
UDDOZWWBHVIGDS-UHFFFAOYSA-N
Catalogue number
GC25450
Brand
GLPBIO
Computed properties PubChem CID 753168 · XLogP 4.1 · TPSA 58.4 Ų · H-bond donors 1
XLogP
4.1
TPSA
58.4 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
26

SMILES CCN(CC)C1=CC=C(C=C1)NC(=O)C2=C(ON=C2C3=CC=CC=C3)C

Computed descriptors from PubChem (CID 753168), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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