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Chemical structure of GSK2646264

GC64889

GSK2646264

Also known as 7-[2-methoxy-6-[(4-methyl-2-pyridinyl)methoxy]phenyl]-2,3,4,5-tetrahydro-1H-3-benzazepine

GSK2646264 (Compound 44) is a potent and selective spleen tyrosine kinase (SYK) inhibitor with a pIC50 of 7·1

ChemicalCAS1398695-47-0MW374.48FormulaC24H26N2O2
CAS number
1398695-47-0
Molecular weight
374.48
Formula
C24H26N2O2
Solubility
DMSO : 50 mg/mL (133·52 mM; ultrasonic and warming and heat to 60°C)
InChIKey
KYANYGKXMNYFBX-UHFFFAOYSA-N
Catalogue number
GC64889
Brand
GLPBIO
Computed properties PubChem CID 60194098 · XLogP 4.2 · TPSA 43.4 Ų · H-bond donors 1
XLogP
4.2
TPSA
43.4 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
28

SMILES CC1=CC(=NC=C1)COC2=CC=CC(=C2C3=CC4=C(CCNCC4)C=C3)OC

Computed descriptors from PubChem (CID 60194098), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.