GC17109
GSK2636771
Also known as 2-methyl-1-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-6-morpholin-4-ylbenzimidazole-4-carboxylic acid
GSK2636771 is a potent adenosine triphosphate competitive oral inhibitor of PI3Kβ, with an IC50 of 5·2 nmol/L against the catalytic subunit, p110β, whilst showing >900-fold selectivity over p110α and p110γ, and >10-fold selectivity over p110δ
ChemicalCAS1372540-25-4MW433.42FormulaC22H22F3N3O3
- CAS number
- 1372540-25-4
- Molecular weight
- 433.42
- Formula
- C22H22F3N3O3
- Solubility
- ≥ 10·825mg/mL in DMSO
- InChIKey
- XTKLTGBKIDQGQL-UHFFFAOYSA-N
- Catalogue number
- GC17109
- Brand
- GLPBIO
Computed properties PubChem CID 56949517 · XLogP 4 · TPSA 67.6 Ų · H-bond donors 1
- XLogP
- 4
- TPSA
- 67.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 8
- Rotatable bonds
- 4
- Heavy atoms
- 31
SMILES CC1=C(C=CC=C1C(F)(F)F)CN2C(=NC3=C(C=C(C=C32)N4CCOCC4)C(=O)O)C
Computed descriptors from PubChem (CID 56949517), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il