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Chemical structure of Incb-086550

GC62688

Incb-086550

Also listed as PD-1/PD-L1-IN-8

PD-1/PD-L1-IN-8 (PD-1/PD-L1-IN-8; example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM

ChemicalCAS2230911-59-6MW693.79FormulaC41H39N7O4
CAS number
2230911-59-6
Molecular weight
693.79
Formula
C41H39N7O4
Solubility
H2O : 83·33 mg/mL (120·11 mM; ultrasonic and adjust pH to 3 with HCl)
InChIKey
QARLNMDDSQMINK-BVRKHOPBSA-N
Catalogue number
GC62688
Brand
GLPBIO
Computed properties PubChem CID 135146787 · XLogP 3.1 · TPSA 152 Ų · H-bond donors 3
XLogP
3.1
TPSA
152 Ų
H-bond donors
3
H-bond acceptors
11
Rotatable bonds
9
Heavy atoms
52

SMILES CC1=C(C=CC=C1C2=NC3=CC(=CC(=C3O2)C#N)CN4CC[C@H](C4)C(=O)O)C5=C(C(=CC=C5)NC6=NC=CC7=CC(=CN=C76)CN8CC[C@H](C8)O)C

Computed descriptors from PubChem (CID 135146787), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.