GC26366
PD-1/PD-L1-IN-33
Also known as 2-methyl-2-[[4-(4-phenyl-2,3-dihydroindol-1-yl)pyrido[3,2-d]pyrimidin-7-yl]methylamino]propan-1-ol
PD-1/PD-L1-IN-33 (Compound N11) is a kind of PD-1/PD-L1 inhibitor· PD-1/PD-L1-IN-33 inhibited the interaction between PD-1 and PD-L1, and IC50 was 6·3nM· PD-1/PD-L1-IN-33 promotes the proliferation, activation and infiltration of T cells into tumor balls· PD-1/PD-L1-IN-33 has immunomodulatory and anticancer activities
ChemicalCAS2975602-78-7MW425.53FormulaC26H27N5O
- CAS number
- 2975602-78-7
- Molecular weight
- 425.53
- Formula
- C26H27N5O
- Solubility
- DMSO ： 100 mg/mL (235·00 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
- InChIKey
- CZQOYRCWBPWJJP-UHFFFAOYSA-N
- Catalogue number
- GC26366
- Brand
- GLPBIO
Computed properties PubChem CID 168510602 · XLogP 3.5 · TPSA 74.2 Ų · H-bond donors 2
- XLogP
- 3.5
- TPSA
- 74.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Rotatable bonds
- 6
- Heavy atoms
- 32
SMILES CC(C)(CO)NCC1=CC2=C(C(=NC=N2)N3CCC4=C(C=CC=C43)C5=CC=CC=C5)N=C1
Computed descriptors from PubChem (CID 168510602), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il