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Chemical structure of PD-1/PD-L1-IN-9

GC62387

PD-1/PD-L1-IN-9

Also known as 2-[[2-methoxy-6-(2-methyl-3-phenylphenyl)-3-pyridinyl]methylamino]ethanol

PD-1/PD-L1-IN-9 is a potent and orally active inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3·8 nM· PD-1/PD-L1-IN-9 can enhance the killing activity of tumor cells by immune cells· PD-1/PD-L1-IN-9 also exhibits significant in vivo antitumor activity in a CT26 mouse model

ChemicalCAS2628506-54-5MW348.44FormulaC22H24N2O2
CAS number
2628506-54-5
Molecular weight
348.44
Formula
C22H24N2O2
Solubility
DMSO ： 100 mg/mL (286·99 mM; Need ultrasonic)
InChIKey
ANLIWBJMRQBWBM-UHFFFAOYSA-N
Catalogue number
GC62387
Brand
GLPBIO
Computed properties PubChem CID 155925913 · XLogP 3.5 · TPSA 54.4 Ų · H-bond donors 2
XLogP
3.5
TPSA
54.4 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
26

SMILES CC1=C(C=CC=C1C2=NC(=C(C=C2)CNCCO)OC)C3=CC=CC=C3

Computed descriptors from PubChem (CID 155925913), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.