Loading...
Chemical structure of PD-1/PD-L1-IN-NP19

GC62502

PD-1/PD-L1-IN-NP19

Also known as 2-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methylamino]-2-methylpropanoic acid

PD-1/PD-L1-IN-NP19 is a PD-1/PD-L1 inhibitor, with an IC50 of 12·5 nM for human PD-1/PD-L1 interaction

ChemicalCAS2377916-66-8MW555.06FormulaC33H31ClN2O4
CAS number
2377916-66-8
Molecular weight
555.06
Formula
C33H31ClN2O4
Solubility
DMSO ： 6·25 mg/mL (11·26 mM; Need ultrasonic)
InChIKey
YZPKZNFXWGTUGO-UHFFFAOYSA-N
Catalogue number
GC62502
Brand
GLPBIO
Computed properties PubChem CID 154573771 · XLogP 4.5 · TPSA 91.6 Ų · H-bond donors 2
XLogP
4.5
TPSA
91.6 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
11
Heavy atoms
40

SMILES CC1=C(C=CC=C1C2=CC=CC=C2)COC3=C(C=C(C(=C3)OCC4=CC(=CC=C4)C#N)CNC(C)(C)C(=O)O)Cl

Computed descriptors from PubChem (CID 154573771), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.