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Chemical structure of WEHI-9625

GC62641

WEHI-9625

Also known as 7-[2-(4-methoxybenzoyl)phenyl]-N-[(4-methylphenyl)methyl]-5,5-dioxo-4H-thieno[3,2-c]thiochromene-2-carboxamide

WEHI-9625 is a tricyclic sulfone, first-in-class inhibitor of apoptosis with an EC50 of 69 nM· WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK· WEHI-9625 is completely inactive against both human BAK and the closely related apoptosis effector BAX

ChemicalCAS2595314-46-6MW593.71FormulaC34H27NO5S2
CAS number
2595314-46-6
Molecular weight
593.71
Formula
C34H27NO5S2
Solubility
DMSO ： 100 mg/mL (168·43 mM; Need ultrasonic)
InChIKey
DQVRUUKJUZNKSW-UHFFFAOYSA-N
Catalogue number
GC62641
Brand
GLPBIO
Computed properties PubChem CID 138805616 · XLogP 6.5 · TPSA 126 Ų · H-bond donors 1
XLogP
6.5
TPSA
126 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
42

SMILES CC1=CC=C(C=C1)CNC(=O)C2=CC3=C(S2)C4=C(C=C(C=C4)C5=CC=CC=C5C(=O)C6=CC=C(C=C6)OC)S(=O)(=O)C3

Computed descriptors from PubChem (CID 138805616), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.