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Chemical structure of WEHI-345

GC18177

WEHI-345

Also known as N-[2-[4-amino-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-2-methylpropyl]pyridine-4-carboxamide

WEHI-345 is an inhibitor of receptor-interacting protein kinase 2 (RIPK2; IC50 = 130 nM in a kinase assay using human recombinant RIPK2)

ChemicalCAS1354825-58-3MW401.5FormulaC22H23N7O
CAS number
1354825-58-3
Molecular weight
401.5
Formula
C22H23N7O
Solubility
DMF： 2 mg/ml,DMSO： 2 mg/ml,Ethanol： slightly soluble
InChIKey
LEBSTCDZKUSVOY-UHFFFAOYSA-N
Catalogue number
GC18177
Brand
GLPBIO
Computed properties PubChem CID 56602554 · XLogP 2.3 · TPSA 112 Ų · H-bond donors 2
XLogP
2.3
TPSA
112 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
30

SMILES CC1=CC=C(C=C1)C2=NN(C3=NC=NC(=C23)N)C(C)(C)CNC(=O)C4=CC=NC=C4

Computed descriptors from PubChem (CID 56602554), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.