Loading...
Chemical structure of WEE1-IN-3

GC62449

WEE1-IN-3

Also known as 1-[6-(2-hydroxypropan-2-yl)-2-pyridinyl]-6-[(2-methylspiro[1,3-dihydroisoquinoline-4,1'-cyclopropane]-7-yl)amino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one

WEE1-IN-3 is a potent Wee1 kinase inhibitor with an IC50 of ＜10 nM· WEE1-IN-3 has anticancer activities

ChemicalCAS2272976-28-8MW497.59FormulaC28H31N7O2
CAS number
2272976-28-8
Molecular weight
497.59
Formula
C28H31N7O2
Solubility
DMSO ： 250 mg/mL (502·42 mM; Need ultrasonic)
InChIKey
JSZFIXAMFNNRKS-UHFFFAOYSA-N
Catalogue number
GC62449
Brand
GLPBIO
Computed properties PubChem CID 137471996 · XLogP 3.3 · TPSA 97.7 Ų · H-bond donors 2
XLogP
3.3
TPSA
97.7 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
37

SMILES CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC5=C(C=C4)C6(CC6)CN(C5)C)O

Computed descriptors from PubChem (CID 137471996), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.