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Chemical structure of EN4

GC62287

EN4

Also known as N-[2-(4-ethoxyphenoxy)phenyl]-4-[(prop-2-enoylamino)methyl]benzamide

EN4 is a covalent ligand that targets cysteine 171 (C171) of MYC· EN4 is selective for c-MYC over N-MYC and L-MYC· EN4 inhibits MYC transcriptional activity, downregulates MYC targets, and impairs tumorigenesis

ChemicalCAS1197824-15-9MW416.47FormulaC25H24N2O4
CAS number
1197824-15-9
Molecular weight
416.47
Formula
C25H24N2O4
Solubility
DMSO ： 250 mg/mL (600·28 mM; Need ultrasonic)
InChIKey
DKOWGKKELPCHEG-UHFFFAOYSA-N
Catalogue number
GC62287
Brand
GLPBIO
Computed properties PubChem CID 45917225 · XLogP 4.3 · TPSA 76.7 Ų · H-bond donors 2
XLogP
4.3
TPSA
76.7 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
9
Heavy atoms
31

SMILES CCOC1=CC=C(C=C1)OC2=CC=CC=C2NC(=O)C3=CC=C(C=C3)CNC(=O)C=C

Computed descriptors from PubChem (CID 45917225), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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