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Chemical structure of EN450

GC74157

EN450

Also known as N-[2-chloro-5-(dimethylsulfamoyl)phenyl]prop-2-enamide

EN450 is a cysteine-reactive covalent molecular glue degrader targeting NF-κB

ChemicalCAS793719-01-4MW288.75FormulaC11H13ClN2O3S
CAS number
793719-01-4
Molecular weight
288.75
Formula
C11H13ClN2O3S
Solubility
DMSO ： 100 mg/mL (346·32 mM; Need ultrasonic)
InChIKey
OXFXDOLAQBMOPH-UHFFFAOYSA-N
Catalogue number
GC74157
Brand
GLPBIO
Computed properties PubChem CID 4877041 · XLogP 1.3 · TPSA 74.9 Ų · H-bond donors 1
XLogP
1.3
TPSA
74.9 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
18

SMILES CN(C)S(=O)(=O)C1=CC(=C(C=C1)Cl)NC(=O)C=C

Computed descriptors from PubChem (CID 4877041), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.