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Chemical structure of JH295 hydrate

GC60959

JH295 hydrate

JH295 hydrate is a potent, irreversible and selective NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 770 nM· JH295 hydrate inhibits cellular Nek2 via alkylation of Cys22· JH295 hydrate is inactive against the mitotic kinases, Cdk1, Aurora B or Plk1, and does not perturb bipolar spindle assembly or the spindle assembly checkpoint

ChemicalMW338.36FormulaC18H18N4O3
CAS number
Molecular weight
338.36
Formula
C18H18N4O3
Catalogue number
GC60959
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.