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Chemical structure of JG-231

GC69312

JG-231

Also known as (2Z,5E)-2-[[3-[(5-bromothiophen-2-yl)methyl]-1,3-thiazol-3-ium-2-yl]methylidene]-5-(6-chloro-3-methyl-1,3-benzothiazol-2-ylidene)-3-ethyl-1,3-thiazolidin-4-one chloride

JG-231 is a JG-98 analogue with anti-cancer properties· It can inhibit the interaction between Hsp70-BAG3· JG-231 has an inhibitory effect on the MDA-MB-231 xenograft model of triple-negative breast cancer (TNBC)

ChemicalCAS1627126-59-3MW619.47FormulaC22H18BrCl2N3OS4
CAS number
1627126-59-3
Molecular weight
619.47
Formula
C22H18BrCl2N3OS4
Solubility
DMSO : 2 mg/mL (3·23 mM; Need ultrasonic)
InChIKey
LFKCNIBJPYBMOM-QPNALZDCSA-M
Catalogue number
GC69312
Brand
GLPBIO
Computed properties PubChem CID 134817195 · TPSA 135 Ų · H-bond donors 0 · H-bond acceptors 7
TPSA
135 Ų
H-bond donors
0
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
33

SMILES CCN1/C(=C/C2=[N+](C=CS2)CC3=CC=C(S3)Br)/S/C(=C/4\N(C5=C(S4)C=C(C=C5)Cl)C)/C1=O.[Cl-]

Computed descriptors from PubChem (CID 134817195), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.