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Chemical structure of JG-98

GC34634

JG-98

Also known as (2Z,5E)-2-[(3-benzyl-1,3-thiazol-3-ium-2-yl)methylidene]-5-(6-chloro-3-methyl-1,3-benzothiazol-2-ylidene)-3-ethyl-1,3-thiazolidin-4-one chloride

JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction· JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages

ChemicalCAS1456551-16-8MW534.54FormulaC24H21Cl2N3OS3
CAS number
1456551-16-8
Molecular weight
534.54
Formula
C24H21Cl2N3OS3
Solubility
DMSO ： 5 mg/mL (9·35 mM)
InChIKey
AUPPGWXGMILTRB-HDPAMLMOSA-M
Catalogue number
GC34634
Brand
GLPBIO
Computed properties PubChem CID 72547053 · TPSA 106 Ų · H-bond donors 0 · H-bond acceptors 6
TPSA
106 Ų
H-bond donors
0
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
33

SMILES CCN1/C(=C/C2=[N+](C=CS2)CC3=CC=CC=C3)/S/C(=C/4\N(C5=C(S4)C=C(C=C5)Cl)C)/C1=O.[Cl-]

Computed descriptors from PubChem (CID 72547053), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.