Loading...
Chemical structure of TP-004

GC60368

TP-004

Also known as (3R)-1-[4-methyl-5-[6-(trifluoromethyl)-1H-indazol-4-yl]pyrimidin-2-yl]pyrrolidin-3-ol

TP-004 is a potent and reversible inhibitor of methionine aminopeptidase 2 (MetAP2), with an IC50 of 6 nM

ChemicalCAS1454299-21-8MW363.34FormulaC17H16F3N5O
CAS number
1454299-21-8
Molecular weight
363.34
Formula
C17H16F3N5O
Solubility
DMSO： 250 mg/mL (688·06 mM)
InChIKey
BNTAEJNPQLMGDJ-LLVKDONJSA-N
Catalogue number
GC60368
Brand
GLPBIO
Computed properties PubChem CID 89794927 · XLogP 2.7 · TPSA 77.9 Ų · H-bond donors 2
XLogP
2.7
TPSA
77.9 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
2
Heavy atoms
26

SMILES CC1=NC(=NC=C1C2=C3C=NNC3=CC(=C2)C(F)(F)F)N4CC[C@H](C4)O

Computed descriptors from PubChem (CID 89794927), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.