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Chemical structure of TP-021

GC66021

TP-021

Also known as 6-[2-chloro-4-nitro-5-(oxan-4-yloxy)anilino]-3,4-dihydro-1H-quinolin-2-one

TP-021 (BCL6-IN-8c) is a potent and orally active B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor with an IC50 of 0·10 μM in cell-free enzyme-linked immunosorbent assay

ChemicalCAS2130878-25-8MW417.84FormulaC20H20ClN3O5
CAS number
2130878-25-8
Molecular weight
417.84
Formula
C20H20ClN3O5
Solubility
DMSO ： ≥ 50 mg/mL (119·66 mM)
InChIKey
RRELDGDKULRRDM-UHFFFAOYSA-N
Catalogue number
GC66021
Brand
GLPBIO
Computed properties PubChem CID 131801156 · XLogP 3.4 · TPSA 105 Ų · H-bond donors 2
XLogP
3.4
TPSA
105 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
29

SMILES C1COCCC1OC2=C(C=C(C(=C2)NC3=CC4=C(C=C3)NC(=O)CC4)Cl)[N+](=O)[O-]

Computed descriptors from PubChem (CID 131801156), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.