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Chemical structure of TP-008

GC75078

TP-008

Also known as 2-[1-[2-(5-chloro-2-fluorophenyl)-5-methyl-4-pyridinyl]-2-oxoimidazo[4,5-c]pyridin-3-yl]acetamide

TP-008 is a potent, selective and orally active (Activin-Like Kinase 5) ALK5 inhibitor with pIC50 and pEC50 values of 7·6 and 6·63, respectively

ChemicalCAS1976038-41-1MW411.82FormulaC20H15ClFN5O2
CAS number
1976038-41-1
Molecular weight
411.82
Formula
C20H15ClFN5O2
Solubility
DMSO： 9·6 mg/mL (23·31 mM; Need ultrasonic and warming)
InChIKey
LVEUPFUJRKZPEN-UHFFFAOYSA-N
Catalogue number
GC75078
Brand
GLPBIO
Computed properties PubChem CID 145925651 · XLogP 2 · TPSA 92.4 Ų · H-bond donors 1
XLogP
2
TPSA
92.4 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
29

SMILES CC1=CN=C(C=C1N2C3=C(C=NC=C3)N(C2=O)CC(=O)N)C4=C(C=CC(=C4)Cl)F

Computed descriptors from PubChem (CID 145925651), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.