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Chemical structure of EM-12

GC49522

EM-12

Also known as 3-(3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione

EM-12 (EM-12), a teratogenic Thalidomide analogue, is more active than Thalidomide and is much more stable for hydrolysis· EM-12 enhances 1,2-dimethylhydrazine-induction of rat colon adenocarcinomas

ChemicalCAS26581-81-7MW244.2FormulaC13H12N2O3
CAS number
26581-81-7
Molecular weight
244.2
Formula
C13H12N2O3
Solubility
DMF: 5 mg/ml,DMF:PBS (pH 7·2) (1:4): 0·2 mg/ml,DMSO: 1 mg/ml
InChIKey
WENKGSGGXGQHSH-UHFFFAOYSA-N
Catalogue number
GC49522
Brand
GLPBIO
Computed properties PubChem CID 91585 · XLogP 0.2 · TPSA 66.5 Ų · H-bond donors 1
XLogP
0.2
TPSA
66.5 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
1
Heavy atoms
18

SMILES C1CC(=O)NC(=O)C1N2CC3=CC=CC=C3C2=O

Computed descriptors from PubChem (CID 91585), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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