Loading...
Chemical structure of SMAD3 Inhibitor, SIS3

GC44903

SMAD3 Inhibitor, SIS3

Also known as 1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one

SMAD3 Inhibitor, SIS3 is a potent and selective inhibitor of Smad3 phosphorylation

ChemicalCAS1009104-85-1MW453.5FormulaC28H27N3O3
CAS number
1009104-85-1
Molecular weight
453.5
Formula
C28H27N3O3
Solubility
30mg/mL in ethanol, or in DMSO, or in DMF
InChIKey
IJYPHMXWKKKHGT-UHFFFAOYSA-N
Catalogue number
GC44903
Brand
GLPBIO
Computed properties PubChem CID 24906269 · XLogP 4.3 · TPSA 56.6 Ų · H-bond donors 0
XLogP
4.3
TPSA
56.6 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
34

SMILES CN1C(=C(C2=C1N=CC=C2)C=CC(=O)N3CCC4=CC(=C(C=C4C3)OC)OC)C5=CC=CC=C5

Computed descriptors from PubChem (CID 24906269), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.