GC62675
SM1-71
Also known as N-[2-[[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
SM1-71 (compound 5) is a potent TAK1 inhibitor, with a Ki of 160 nM, it also can covalently inhibit MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2· SM1-71 can inhibit proliferation of multiple cancer cell lines
ChemicalCAS2088179-99-9MW463.96FormulaC24H26ClN7O
- CAS number
- 2088179-99-9
- Molecular weight
- 463.96
- Formula
- C24H26ClN7O
- InChIKey
- SCMLGVPMSXTUNC-UHFFFAOYSA-N
- Catalogue number
- GC62675
- Brand
- GLPBIO
Computed properties PubChem CID 131801160 · XLogP 4.3 · TPSA 85.4 Ų · H-bond donors 3
- XLogP
- 4.3
- TPSA
- 85.4 Ų
- H-bond donors
- 3
- H-bond acceptors
- 7
- Rotatable bonds
- 7
- Heavy atoms
- 33
SMILES CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NC(=O)C=C)Cl
Computed descriptors from PubChem (CID 131801160), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il