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Chemical structure of CC-92480

GC39169

CC-92480

Also known as 4-[4-[[4-[[2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-3H-isoindol-4-yl]oxymethyl]phenyl]methyl]piperazin-1-yl]-3-fluorobenzonitrile

CC-92480 (CC-92480), a cereblon E3 ubiquitin ligase modulating drug (CELMoD), acts as a molecular glue· CC-92480 shows high affinity to cereblon, resulting in potent antimyeloma activity

ChemicalCAS2259648-80-9MW567.61FormulaC32H30FN5O4
CAS number
2259648-80-9
Molecular weight
567.61
Formula
C32H30FN5O4
Solubility
DMSO: 5 mg/mL (8·81 mM; ultrasonic and warming and heat to 60°C)
InChIKey
YTINZZFBHWSAGL-NDEPHWFRSA-N
Catalogue number
GC39169
Brand
GLPBIO
Computed properties PubChem CID 137379043 · XLogP 2.9 · TPSA 106 Ų · H-bond donors 1
XLogP
2.9
TPSA
106 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
42

SMILES C1CC(=O)NC(=O)[C@H]1N2CC3=C(C2=O)C=CC=C3OCC4=CC=C(C=C4)CN5CCN(CC5)C6=C(C=C(C=C6)C#N)F

Computed descriptors from PubChem (CID 137379043), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.