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Chemical structure of CC-90005

GC62612

CC-90005

Also known as 2-[[4-(2,2-difluoropropoxy)pyrimidin-5-yl]methylamino]-4-[[(1R,4S)-4-hydroxy-3,3-dimethylcyclohexyl]amino]pyrimidine-5-carbonitrile

CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-θ (PKC-θ), with an IC50 of 8 nM

ChemicalCAS1799574-70-1MW447.48FormulaC21H27F2N7O2
CAS number
1799574-70-1
Molecular weight
447.48
Formula
C21H27F2N7O2
Solubility
DMSO ： 62·5 mg/mL (139·67 mM; Need ultrasonic)
InChIKey
FMKGJQHNYMWDFJ-CVEARBPZSA-N
Catalogue number
GC62612
Brand
GLPBIO
Computed properties PubChem CID 118162109 · XLogP 3.7 · TPSA 129 Ų · H-bond donors 3
XLogP
3.7
TPSA
129 Ų
H-bond donors
3
H-bond acceptors
11
Rotatable bonds
8
Heavy atoms
32

SMILES CC1(C[C@@H](CC[C@@H]1O)NC2=NC(=NC=C2C#N)NCC3=CN=CN=C3OCC(C)(F)F)C

Computed descriptors from PubChem (CID 118162109), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.