Loading...
Chemical structure of ONC206

GC38935

ONC206

Also known as 11-benzyl-7-[(2,4-difluorophenyl)methyl]-2,5,7,11-tetrazatricyclo[7.4.0.02,6]trideca-1(9),5-dien-8-one

ONC206 is a dopamine D2-like receptor (DRD2/3/4) antagonist belonging to the imipridone class of drugs, with an IC50 of 0·21μM to 0·32μM

ChemicalCAS1638178-87-6MW408.44FormulaC23H22F2N4O
CAS number
1638178-87-6
Molecular weight
408.44
Formula
C23H22F2N4O
Solubility
DMSO： 100 mg/mL (244·83 mM)
InChIKey
ITMGVSSHWMTJRR-UHFFFAOYSA-N
Catalogue number
GC38935
Brand
GLPBIO
Computed properties PubChem CID 135297777 · XLogP 2.2 · TPSA 39.2 Ų · H-bond donors 0
XLogP
2.2
TPSA
39.2 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
30

SMILES C1CN(CC2=C1N3CCN=C3N(C2=O)CC4=C(C=C(C=C4)F)F)CC5=CC=CC=C5

Computed descriptors from PubChem (CID 135297777), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.