GC73707
ON 108600
Also known as (2Z)-6-[(2,6-dichlorophenyl)methylsulfonyl]-2-[(4-hydroxy-3-nitrophenyl)methylidene]-4H-1,4-benzothiazin-3-one
ON 108600 is a inhibitor for CK2 (Casein Kinase2)/TNIK/DYRK1 , with the IC50s for DYRK1A/DYRKB, DYRK2, CK2α1/CK2α2, and TNIK of 0·016 μm/0·007 μM, 0·028 μM, 0·05 μM/0·005 μM, and 0·005 μM, respectively
ChemicalCAS1585246-23-6MW537.39FormulaC22H14Cl2N2O6S2
- CAS number
- 1585246-23-6
- Molecular weight
- 537.39
- Formula
- C22H14Cl2N2O6S2
- Solubility
- DMSO ： 100 mg/mL (186·08 mM; Need ultrasonic)
- InChIKey
- DOMBZVXKSRQDOJ-NKVSQWTQSA-N
- Catalogue number
- GC73707
- Brand
- GLPBIO
Computed properties PubChem CID 90074871 · XLogP 5.6 · TPSA 163 Ų · H-bond donors 2
- XLogP
- 5.6
- TPSA
- 163 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Rotatable bonds
- 4
- Heavy atoms
- 34
SMILES C1=CC(=C(C(=C1)Cl)CS(=O)(=O)C2=CC3=C(C=C2)S/C(=C\C4=CC(=C(C=C4)O)[N+](=O)[O-])/C(=O)N3)Cl
Computed descriptors from PubChem (CID 90074871), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il